Ultra-processed food (UPF) is linked to harm in every major organ system of the human body and poses a seismic threat to global health, according to the world’s largest review. UPF is also rapidly displacing fresh food in the diets of children and adults on every continent and is associated with an increased risk of a dozen health conditions, including obesity, type 2 diabetes, heart disease and depression.

In the UK and US, over half the average diet is UPF, with some disadvantaged groups consuming up to 80%. Corporations drive this rise with aggressive tactics and hinder regulation.

The Lancet series reveals that ultra-processed foods harm major organs and humans aren’t adapted to them. It suggests policies to regulate UPF production, marketing, and consumption. Current global public health efforts are in early stages, similar to early tobacco control

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